Top 10 Healthcare Companies in USA (2025)
Here are the top 10 healthcare companies in the United States, ranked by revenue:
UnitedHealth Group
- Revenue: $324.16 billion (2022)
- Headquarters: Minnetonka, Minnesota
- Overview: A diversified health and well-being company offering health care coverage and benefits services through UnitedHealthcare, and information and technology-enabled health services through Optum.
- Revenue: $322.46 billion (2022)
- Headquarters: Woonsocket, Rhode Island
- Overview: Operates a chain of pharmacies and retail clinics; provides health insurance services through Aetna, and pharmacy benefit management through CVS Caremark.
McKesson Corporation
- Revenue: $263.96 billion (2022)
- Headquarters: Irving, Texas
- Overview: Distributes pharmaceuticals and provides health information technology, medical supplies, and care management tools.
AmerisourceBergen (now Cencora Inc.)
- Revenue: $238.58 billion (2022)
- Headquarters: Conshohocken, Pennsylvania
- Overview: Distributes pharmaceutical products and provides related services to healthcare providers and pharmaceutical manufacturers.
Cardinal Health
- Revenue: $181.36 billion (2022)
- Headquarters: Dublin, Ohio
- Overview: Distributes pharmaceuticals and medical products; offers services to hospitals, pharmacies, and other healthcare providers.
Cigna
- Revenue: $180.51 billion (2022)
- Headquarters: Bloomfield, Connecticut
- Overview: Provides health insurance and related services, including medical, dental, disability, life, and accident insurance.
Elevance Health (formerly Anthem Inc.)
- Revenue: $156.59 billion (2022)
- Headquarters: Indianapolis, Indiana
- Overview: Offers health insurance plans and related services; operates Blue Cross Blue Shield plans in multiple states.
Centene Corporation
- Revenue: $144.54 billion (2022)
- Headquarters: St. Louis, Missouri
- Overview: Provides managed care services to government-sponsored healthcare programs, focusing on under-insured and uninsured individuals.
Pfizer
- Revenue: $100.33 billion (2022)
- Headquarters: New York, New York
- Overview: Develops and manufactures pharmaceutical products across various therapeutic areas, including vaccines and oncology.
Johnson & Johnson
- Revenue: $94.94 billion (2022)
- Headquarters: New Brunswick, New Jersey
- Overview: Engages in the research, development, manufacture, and sale of a broad range of healthcare products, including pharmaceuticals, medical devices, and consumer health products.
These companies play significant roles in the U.S. healthcare system, offering a wide range of services and products that contribute to the industry’s overall landscape.
Here is expanded information about each of the top 10 healthcare companies in the U.S., including their history, services, and unique contributions to the healthcare industry:
UnitedHealth Group
- Founded: 1977
- Business Segments: UnitedHealthcare (health benefits) and Optum (healthcare services and technology).
- Key Products/Services: Employer and individual health plans, Medicare and Medicaid services, health technology solutions.
- Unique Contributions: Innovative use of data analytics in healthcare delivery through Optum; strong presence in value-based care initiatives.
CVS Health
- Founded: 1963
- Business Segments: Retail pharmacies, healthcare clinics, health insurance (Aetna), and pharmacy benefits management (CVS Caremark).
- Key Products/Services: Prescription drug services, retail health services, specialty pharmacy, and MinuteClinic walk-in medical services.
- Unique Contributions: Integrated healthcare approach combining pharmacy, insurance, and retail healthcare services under one brand.
McKesson Corporation
- Founded: 1833
- Key Services: Pharmaceutical distribution, health IT systems, oncology and specialty healthcare solutions.
- Unique Contributions: Leader in supply chain innovation for pharmaceutical distribution and pioneering healthcare analytics and automation technologies.
AmerisourceBergen (now Cencora)
- Founded: 2001 (merger of AmeriSource Health and Bergen Brunswig)
- Key Services: Specialty drug distribution, consulting services for pharmaceutical manufacturers.
- Unique Contributions: Major distributor of cancer-related and specialty drugs, leading innovations in global healthcare supply chains.
Cardinal Health
- Founded: 1971
- Key Services: Pharmaceutical and medical product distribution, laboratory solutions, healthcare consulting.
- Unique Contributions: Development of innovative surgical products and advanced logistics solutions for healthcare systems.
- Founded: 1792 (originally INA, merged with Connecticut General in 1982)
- Key Products/Services: Health, dental, vision, and disability insurance; global health services.
- Unique Contributions: Leadership in global health insurance markets, commitment to mental health and holistic wellness.
Elevance Health (formerly Anthem Inc.)
- Founded: 1944
- Key Services: Health insurance and related services under Blue Cross Blue Shield brands in 14 states.
- Unique Contributions: Emphasis on personalized healthcare solutions and partnerships promoting community health initiatives.
Centene Corporation
- Founded: 1984
- Key Services: Managed care for government-sponsored programs including Medicaid and the Health Insurance Marketplace.
- Unique Contributions: Focus on the underinsured and partnerships for community health improvement, extensive Medicaid management expertise.
Pfizer
- Founded: 1849
- Key Products: Vaccines (e.g., COVID-19 vaccine), oncology drugs, cardiovascular treatments, and more.
- Unique Contributions: Major contributor to global healthcare with innovations like mRNA vaccine technology and leadership in oncology research.
Johnson & Johnson
- Founded: 1886
- Key Products: Consumer health products (Tylenol, Band-Aid), pharmaceuticals, and medical devices.
- Unique Contributions: Leader in medical innovation, surgical technologies, and consumer wellness products. Famous for its ethical commitment to healthcare with a strong focus on patient safety.
These companies offer diverse services and products across pharmaceutical manufacturing, insurance, medical devices, and health services, significantly impacting global health outcomes.